Update your system and install the latest version of UIFlow or M5Burner if they are not running on Windows 10. Ensure that the CP210x USB to UART drivers have been installed. Ensure that the software is run as an Administrator and that conflicting applications using the COM port are closed. Disable your antivirus/firewall temporarily and reinstall the software if necessary. As a result of these steps, connectivity and execution issues can be resolved, ensuring that M5Stack tools operate smoothly.