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Malegra FXT Plus is usually taken 1 to 3 hours before sexual activity. It can be taken with or without food, but heavy meals may delay its effects. Common side effects include headache, flushing, dizziness, nasal congestion, and nausea. Because it combines two active drugs, it’s important to use Malegra FXT Plus under medical supervision, especially if you are on other medications or have underlying health issues. This dual-action formula makes Malegra FXT Plus a popular choice for men facing both ED and PE. Sildenafil typically starts working within 30 to 60 minutes, with effects lasting around 4 to 6 hours, while dapoxetine helps delay ejaculation within 1 to 3 hours of taking the medication.