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Cenforce 130 mg is considered a high-strength dose, typically prescribed for men who do not respond adequately to standard doses such as 50 mg or 100 mg. It is usually taken 30–60 minutes before sexual activity, with effects lasting 4–6 hours, depending on individual metabolism and health conditions. It should not be taken more than once in 24 hours, and dosage adjustments must always be guided by a healthcare professional. Because Cenforce 130 mg contains a high concentration of sildenafil, blood vessels in the penis may remain dilated for longer periods. In rare cases, this can lead to prolonged erections (priapism), which can be painful and potentially cause tissue damage if not treated promptly.