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The active component in Zhewitra, Vardenafil works by blocking the enzyme PDE5, which leads to increased levels of cyclic guanosine monophosphate (cGMP) in the body. This compound is crucial for smooth muscle relaxation and blood vessel dilation, particularly in the penile region.Zhewitra is indicated for the management of erectile dysfunction, enabling men to achieve and maintain an erection suitable for sexual intercourse.